倪祁健 博士（副教授，硕士生导师）
办公室:花津校区新浦新京官网礼勤楼1116
实验室:花津校区新浦新京官网礼勤楼1123-1124
Email:qijianni@ahnu.edu.cn
教育经历
2004.09-2008.07 安徽师范大学 理学学士（导师：罗时忠）
2008.09-2011.07 大连理工大学 工学硕士（导师：刘春）
2011.09-2015.07 德国亚琛工业大学 理学博士（导师：Dieter Enders）
工作经历
主持项目
2021.1-2023.12,国家自然科学青年基金“不对称有机小分子催化/去芳构化策略构建苯并含氮杂环类化合物”(22001010),项目负责人
2019.7-2021.6 安徽省自然科学青年基金“不对称脱羧环化构建中环含氮杂环化合物”(1908085QB55),项目负责人
2018年安徽省平台引才资助经费，项目负责人
安徽师范大学博士科研启动基金，项目负责人
研究领域
课题组成员
在读硕士生：
23级（程圆圆、何柳、李聪）
24级（张静、刘从辉）
25级（李逛成、刘鑫涛）
已毕业硕士生：
18级：王旭阳(南开大学攻读博士)、曾达（江苏中烟工业有限责任公司淮阴卷烟厂）、许磊（南京工业大学攻读博士）
19级：朱智铭(华中师范大学攻读博士)、许方方、范彦君
20级：张莅蓉、姜旭华、秦唯
21级：张璇(陕西师范大学攻读博士)、张晗、邵雪城
22级: 吴倩玲、高成(中国海洋大学攻读博士)、占雯燕
已发表论文
31) Cong Li, Qijian Ni, and Xiaoxiao Song*. Enantioselective Synthesis of Seven-Membered Bridged Biaryls via Pd-Catalyzed Asymmetric Annulative Allylic Alkylation. Org. Lett. 2026, DOI:10.1021/acs.orglett.6c00249.link
30）Yuanyuan Cheng,Jing Li, and Qijian Ni*.Enantioselective Access to Lactam-Fused Eight-Membered Bridged Biaryls via N?Heterocyclic Carbene-Catalyzed [5 + 3]-Domino Annulation. Org. Lett. 2025, 27, 13579-13584.link
29）Yuanyuan Cheng, Xuecheng Shao, and Qijian Ni*. Organocatalytic Asymmetric [5 + 3] Domino Annulation: Direct Access to Enantioenriched Eight-Membered Bridged Dihydroazocino[4,5?b]indolizines.Org. Lett. 2025, 27, 13061-13066.link
28）Cheng Gao, Yuan Li,Gen Luo,* Qijian Ni*.Chiral Phosphoric Acid-Catalyzed Asymmetric Doyle Indolization: Enantiodivergent Access to Indolizinylindoles. Org. Lett. 2025, 27, 9576-9581.link
27）Xuan Zhang, Xu-Hua Jiang, Chun-Dong Huang, Cheng Gao, Shao-Fei Ni*, and Qi-Jian Ni*. Organocatalytic Access to C1-Functionalized Indolizines via Remote Stereocontrolled Construction of Axially Chiral Allenes. Chin. J. Chem. 2025, 43, 2749-2755.link
26）Qianling Wu, Xiaojing Wang, and Qijian Ni*.Dearomative Ring-Opening of N?Fused Heteroarenes: Access to Tetrasubstituted Alkenes and Ketimines.J. Org. Chem. 2025, 90, 5720–5724.link
25）Zhiming Zhu, Qianling Wu, Xiaoxiao Song* and Qijian Ni*. Thermodynamic Controlled Regioselective C1-Functionalization of Indolizines with 3-Hydroxyisoindolinones via Br?nsted Acid Catalyzed aza-Friedel–Crafts Reaction, J. Org. Chem. 2024, 89,2794-2799.link
24)Xuan Zhang, Xiaoxiao Song and Qijian Ni*.Organocatalytic regio- and enantioselective C1-arylation of β,γalkynyl-α-imino esters with pyrrolo[2,1-a]isoquinolines,Chem. Commun.2024,60, 831-834.link
23) Xiaoxiao Song*, Wei Qin, Xuyang Wang, Gen Luo, and Qijian Ni*.Bifunctional Squaramide-Catalyzed Asymmetric Cascade Reaction of Benzothiazoles with 2-Nitroallylic Acetates or Nitroenynes,Org. Lett.2023,25, 9164-9169.link
22)Qijian Ni*, Lirong Zhang, Zhiming Zhu, Xiaoxiao Song*.Formal [5+2] cycloaddition of ortho-indolizinyl anilines with cyclo-pentendiones: access to planar indolizine-fused azepines,Org. Chem. Front.2023,10,2526-2531.link
21)Qijian Ni*,Fangfang Xu, Xiaoxiao Song*.Diastereoselective and E/Z-Selective Synthesis of Functionalized Quinolizine Scaffolds via the Dearomative Annulation of 2-Pyridylacetates with Nitroenynes,J. Org. Chem. 2022,87, 9507-9517.link
20)Xiaoxiao Song*, Yanjun Fan, Zhiming Zhu,Qijian Ni*.Chiral Phosphoric Acid Catalyzed Asymmetric Arylation of Indolizines: Atroposelective Access to Axially Chiral 3-Arylindolizines,Org.Lett.2022,24, 2315-2320.link
19)Qijian Ni*, Zhiming Zhu, Yanjun Fan, Xiaoyun Chen, Xiaoxiao Song*.Chiral Phosphoric Acid Catalyzed Desymmetrization of Cyclopentendiones via Friedel-Crafts Conjugate Addition of Indolizines,Org.Lett.2021,23,9548-9553.link
18)Qijian Ni*, Xuyang Wang, Da Zeng, Qianling Wu, Xiaoxiao Song*.Organocatalytic Asymmetric Synthesis of Aza-Spirooxindoles via Michael/Friedel-Crafts Cascade Reaction of 1,3-Nitroenynes and 3-Pyrrolyloxindoles,Org.Lett.2021,23, 2273-2278.link
17)Qijian Ni, Xiaoxiao Song, Chin Wen Png, Yongliang Zhang*, Yu Zhao*. Access to Substituted Cyclobutenes by Tandem [3,3]-Sigmatropic Rearrangement/[2+2] Cycloaddition of Dipropargylphosphonates under Ag/Co Relay Catalysis,Chem. Sci.,2020,11,12329-12335.link
16) Xiaoxiao Song*, Lei Xu,Qijian Ni*. Highly diastereoselective synthesis of 3-methylenetetrahydropyrans by palladium catalyzed oxa-[4 + 2] cycloaddition of 2-alkenylbenzothiazoles,Org. Biomol. Chem.2020,18, 6617-6621.link
15)Qijian Ni*, Xuyang Wang, Fangfang Xu, Xiaoyun Chen, Xiaoxiao Song*. Organocatalytic asymmetric [4+2] cyclization of 2-benzothiazolimines with azlactones: access to chiral benzothiazolopyrimidine derivatives,Chem. Commun.2020,56, 3155-3158.link
14) Xiaoxiao Song*, Mengjie Gu, Xiaoyun Chen, Lei Xu,Qijian Ni*. Highly Stereoselective Palladium-Catalyzed [3+2] Cycloaddition of Vinyl Epoxides and N-Benzothiazolimine,Asian J. Org. Chem.2019,8, 2180-2183.link
13) Jiayu Liao,Qijian Ni, Yu Zhao*. Catalyst-Enabled Scaffold Diversity: Highly Chemo- and Stereoselective Synthesis of Tricyclic Ketals and Triarylmethanes,Org. Lett.2017,19, 4074-4077.
12) Tao Shu,Qijian Ni, Xiaoxiao Song, Kun Zhao, Tianyu Wu, Rakesh Puttreddy, Kari Rissanen, Dieter Enders*. Asymmetric synthesis of cyclopentanes bearing four contiguous stereocenters via an NHC-catalyzed Michael/Michael/esterification domino reaction,Chem. Commun.2016,52, 2609-2611.
11)Qijian Ni, Jiawen Xiong, Xiaoxiao Song, Gerhard Raabe, Dieter Enders*. NHC-Catalyzed Activation of α,β-Unsaturated N-Acyltriazoles: An Easy Access to Dihydropyranones,Chem. Commun.2015,51, 14628-14631.
10)Qijian Ni, Jiawen Xiong, Xiaoxiao Song, Gerhard Raabe, Dieter Enders*. NHC-Catalyzed Enantioselective Annulation of Benzothiazolyl Ethyl Acetates with 2-Bromoenals,Synlett2015,26, 1465-1469.
9)Qijian Ni, Xiaoxiao Song, Jiawen Xiong, Gerhard Raabe, Dieter Enders*. Regio- and stereoselective synthesis of benzothiazolo-pyrimidinones via an NHC-catalyzed Mannich/lactamization domino reaction,Chem. Commun.2015,51, 1263-1266.
8) Lei Wang,Qijian Ni, Marcus Blümel, Tao Shu, Gerhard Raabe, Dieter Enders*. NHC-Catalyzed Asymmetric Synthesis of Functionalized Succinimides from Enals and α-Ketoamides,Chem. Eur. J.2015,21, 8033-8037.
7)Qijian Ni, Xiaoxiao Song, Gerhard Raabe, Dieter Enders*. N-Heterocyclic Carbene-Catalyzed Enantioselective Annulation of Indolin-3-ones with Bromoenals,Chem. Asian J.2014,9, 1535-1538.
6) Xiaofei Zeng,Qijian Ni, Gerhard Raabe, Dieter Enders*. A Branched Domino Reaction: Asymmetric Organocatalytic Two-Component Four-Step Synthesis of Polyfunctionalized Cyclohexene Derivatives,Angew. Chem. Int. Ed.2013,52, 2977-2980.
5)Qijian Ni, Huan Zhang, André Grossmann, Charles C. J. Loh, Carina Merkens, Dieter Enders*. Asymmetric Synthesis of Pyrroloindolones by N-Heterocyclic Carbene Catalyzed [2+3] Annulation of α-Chloroaldehydes with Nitrovinylindoles,Angew. Chem. Int. Ed.2013,52, 13562-13566. (highlighted in SYNFACTS 2014, 212)
4) Chun Liu*,Qijian Ni, Fanying Bao, Jieshan Qiu. A simple and efficient protocol for the palladium-catalyzed ligand-free Suzuki reaction at room temperature in aqueous DMF,Green Chem.2011,13, 1260-1266.
3) Chun Liu*,Qijian Ni, Jieshan Qiu*. Very Fast, Ligand-Free and Aerobic Protocol for the Synthesis of 4-Aryl-Substituted Triphenylamine Derivatives,Eur. J. Org. Chem.2011, 3009-3015.
2) Chun Liu*,Qijian Ni, Pingping Hu, Jieshan Qiu. Oxygen-promoted PdCl2-catalyzed ligand-free Suzuki reaction in aqueous media,Org. Biomol. Chem.2011,9, 1054-1060.
1) 刘春*,倪祁健, 胡萍萍, 袁浩，金子林。水溶性亚胺配体/钯催化的室温Suzuki反应,催化学报,2010,31,1277-1280.
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新加坡国立大学赵宇教授
德国亚琛工业大学Dieter Enders教授
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